Why investors are taking another look at kidney disease

why-investors-are-taking-another-look-at-kidney-disease

October 22, 2026 | 

1 min read | 

In this episode of Denatured, you’ll hear from Bruce Culleton, CEO at ProKidney and Demetri Maxim, CEO at Nephrogen. We discuss why kidney disease has long been a hard target for cell and gene therapies, and what new delivery strategies, therapeutic approaches and regulatory clarity mean for commercially viable products.

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In this episode of Denatured, you’ll listen to Bruce Culleton, CEO at ProKidney and Demetri Maxim, CEO at Nephrogen. We explore why kidney disease has historically been a difficult target for cell and gene therapies, and how advances in delivery, therapeutic modalities and evolving regulatory frameworks are shaping the path to commercially viable treatments.

Host

⁠Jennifer C. Smith-Parker, Director of Insights, BioSpace

Guests

Bruce Culleton, CEO, ProKidney

Demetri Maxim, CEO, Nephrogen

Disclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

Jennifer C. Smith-Parker is Director of Insights at BioSpace. She has been been immersed for 20 years in healthcare, first as a journalist and editor before pivoting to corporate, brand, and product communications. A skilled storyteller, she is adept at creating diverse content across platforms and crafting narratives that drive engagement, strengthen reputation, and deliver measurable growth. You can reach her at Jennifer.Smith-Parker@BioSpace.com.

The BioSpace Insights teams performs research and analysis on industry trends for BioSpace and clients, producing industry reports, podcasts, events and articles.